Immune Regulation
Rather than suppressing the entire immune system, Dr. Riella’s lab employs unique methods to enhance the regulatory arm of the immune system. This approach fosters a healthier balance and reduces the toxicity associated with immunosuppressive medications. They are actively investigating regulatory immune pathways and cells, such as regulatory T cells, PD1, CTLA4, and Notch pathways. Their groundbreaking research has been published in reputable scientific journals such as Circulation, Nature Comm, JCI, JCI Insight, American Journal Transp, and Transplantation.