Our lab studies innovative ways to regulate the immune system to better manage and treat transplanted patients.

Our research portfolio is diverse, but our goal is singular: to redefine the boundaries of transplant medicine.

World’s First Genetically-Edited Pig Kidney Transplant into Living Recipient Performed at Massachusetts General Hospital.

Under the leadership of Leonardo V. Riella, MD, PhD, Medical Director for Kidney Transplantation, a genetically-edited pig kidney with 69 genomic edits was successfully transplanted into a living patient.

Recent Publications

News

Videos

Great case @AlJurdi highlighting the importance of identifying the underlying cause of C3 glomerulonephritis posttx for effective treatment.On this case an IgG λ monoclonal gammopathy treated plasma cell clone-directed therapy. @MGHKidneys @mgh_transplant

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Successful Treatment of Posttransplant Monoclonal Gammopathy-associated C3 Glomerulopathy With...

www.ncbi.nlm.nih.gov

Learn more about our kidney #xenotransplant @mgh_transplant
This short video provides an overview of the rationale, the details about the immunosuppression used, and the precautions taken in our study. Click on the second video in the video section @ https://www.leoriella.com

With tremendous joy, I share that our patient who received a gene-edited pig kidney transplant was discharged home today after removal of his dialysis access. We hope that this is a first step that will bring hope to many patients waiting for a kidney transplant #xenotransplant

Updates on ABMR, recurrent disease, cardiometabolic disease and machine perfusion strategies at the #tts2024 PGC @ttsorg @ttsecmc https://tts2024.org/program/post-graduate-course-sept-22

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